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Figure 1 | BMC Surgery

Figure 1

From: Ca2+-dependent nitric oxide release in the injured endothelium of excised rat aorta: a promising mechanism applying in vascular prosthetic devices in aging patients

Figure 1

NO production in rat aortic endothelium. A, exposition to SNAP (500 μM) caused an increase in DAF-FM fluorescence in native rat aortic endothelium in situ. The trace is the mean±SE of 11 cells from the same visual field. B, ATP (300 μM) induced an elevation in intracellular NO (closed circles) that was dramatically hampered when the rings were pre-treated with L-NAME (5 mM) for 40 min (white circles). The traces are the mean±SE, respectively, of 10 (PSS) and 8 (L-NAME) cells from two aortic rings harvested from the same animal on the same day.

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