Antecedent event | Associated variable | No. (%) or mean with antecedent event | No. (%) or mean with other antecedent events combined | OR; CI; P-value (X2, Fisher’s exact or t-test) | Adjusted P-value (multivariable logistic regression) |
---|---|---|---|---|---|
aAcute idiopathic soft tissue infection/ulcer (n = 39) | Male gender | 19/39 (48.7 %) | 27/89 (30.3 %) | 2.18; 1.01-4.73; 0.046 | 0.025 |
bNon-ulcerative structural foot abnormalities | 16/33 (48.5 %) | 12/54 (22.2 %) | 3.29; 1.29–8.14; 0.011 | 0.031 | |
Chronic neuropathic ulcer (n = 30) | cDiabetes > 5 years | 30/30 (100 %) | 83/97 (85.6 %) | P = 0.027 | |
dPrevious infection affected limb | 25/30 (83.3 %) | 20/97 (20.6 %) | 19.25; 6.54–57; <0.001 | d < 0.001 | |
ePrevious infection either limb | 29/30 (96.7 %) | 36/97 (37.1 %) | 49.14; 6.42–376; <0.001 | e < 0.001 | |
Insulin dependent | 24/30 (80 %) | 57/97 (58.8 %) | 2.81; 1.05–7.49; 0.034 | 0.042 | |
fPeripheral sensory neuropathy | 30/30 (100 %) | 77/97 (79.4 %) | P = 0.007 | ||
Closed puncture wound (n = 25) | gPrevious infection affected limb | 4/25 (16 %) | 41/103 (39.8 %) | 0.29; 0.09–0.9; 0.025 | g0.007 |
hPrevious infection either limb | 6/25 (24 %) | 59/103 (57.3 %) | 0.24; 0.087–0.64 0.003 | h0.001 | |
Insulin dependent | 10/25 (40 %) | 72/103 (69.9 %) | 0.29; 0.12–0.71; 0.005 | 0.003 | |
Time to first presentation to a doctor | 4.7 days | 7.6 days | 0.9; 0.81–1.005; 0.056 | 0.015 |