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Table 2 Factors associated with nodal skip metastasis

From: Nodal skip metastasis in thoracic esophageal squamous cell carcinoma: a cohort study

 

Non-NSM

NSM

p-value

Number

72

16

-

Age (years)a

63 (57–70)

59 (54–69)

0.64

Sex Male: Female

59:13

12:4

0.50

Advanced liver disease

15 (20.8)

3 (18.8)

0.99

Pulmonary disease

14 (19.4)

3 (18.8)

0.99

Tumor location:

  

0.02

Upper thoracic esophagus

10 (13.9)

4 (25.0)

Middle thoracic esophagus

28 (38.9)

10 (62.5)

Lower thoracic esophagus

34 (47.2)

2 (12.5)

Tumor differentiation:

  

0.21

Well

11 (15.3)

5 (31.3)

Moderate

47 (65.3)

10 (62.5)

Poor

14 (19.4)

1 (6.2)

Tumor length (mm)a

50 (40–70)

50 (35–50)

0.22

Preoperative clinical N stage:

  

0.04

cN+

35 (48.6)

3 (18.8)

cN0

37 (51.4)

13 (81.2)

Pathologic T stage:

  

0.99

pT1-pT2

17 (23.6)

4 (25.0)

pT3-pT4

55 (76.4)

12 (75.0)

Harvested lymph nodesa

17 (12–25)

18 (13–23)

0.72

Metastatic lymph nodesa

1 (1–3)

2 (1–5)

0.01

  1. Data expressed as n (%) or amedian(IQR), NSM nodal skip metastasis