Skip to main content

Table 3 Exclusion criteria

From: A multicenter randomized clinical trial investigating the cost-effectiveness of treatment strategies with or without antibiotics for uncomplicated acute diverticulitis (DIABOLO trial)

1. Previous radiological (US and/or CT) proven episode of diverticulitis;

2. US and/or CT suspicion of colonic cancer

3. Inflammatory bowel disease (ulcerative colitis, Crohn's disease);

4. Hinchey stages 2, 3 and 4 or "severe" diverticulitis according to the Ambrosetti criteria, which require surgical or percutaneous treatment;

5. Other disease with expected survival of less than 6 months;

6. Contraindication for the use of the study medication (e.g. patients with advanced renal failure or allergy to antibiotics used in this study);

7. Pregnancy;

8. ASA (American Society of Anesthesiologists) classification > III;

9. Immunocompromised patient; (i.e., haematological malignancies, AIDS patients with low CD4+ counts, transplantation, chemotherapy, splenectomy, long-term corticosteroid use and genetic disorders such as severe combined immunodeficiency.

10. Clinical suspicion of bacteraemia (i.e. sepsis);

11. The ability of reading/understanding and filling in the questionnaires.

12. Antibiotic use in the 4 weeks prior to inclusion