From: Use of Floseal®, a human gelatine-thrombin matrix sealant, in surgery: a systematic review
Author and year | Comparator and patients per arm (n) | Primary endpoint | Principal results |
---|---|---|---|
Comadoll 2012[11] | Floseal® (184) | Pre- and postoperative decreases in haemoglobin decreases | Floseal® resulted in less reduction in haemoglobin than did the use of conventional haemostatic methods (p < 0.0001). |
Conventional haemostatic methods (Electrocautery, suturing, or manual compression) (165) | |||
Kim 2012[9] | Floseal® (97) | Blood loss measured through drain output | Floseal® had no demonstrable effect on blood loss, as measured through drain output. |
Electrocautery (99) | |||
Velyvis 2012[10] | Floseal® (83) | Blood loss measured through drain output | Floseal® significantly reduced blood loss (p = 0.0001) and blood transfusion requirements (p = 0.07). |
Conventional method (100) |