Table 3 Univariate and multivariate Cox proportional hazards regression for disease-free survival
From: Impact of ABO blood group on the prognosis of patients undergoing surgery for esophageal cancer
Variables | Category | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
HR | 95 % CI | P-value | HR | 95 % CI | P-value | ||
T stage | pT1+ pT2 | 1.00 | 1.00 | ||||
pT3+ pT4 | 2.24 | 1.72–2.90 | <0.001 | 1.79 | 1.21–2.64 | 0.004 | |
N stage | N0 | 1.00 | 1.00 | ||||
N1-3 | 2.38 | 1.83–3.09 | <0.001 | 1.66 | 0.82–3.34 | 0.156 | |
TNM stage | I + II | 1.00 | 1.00 | ||||
III | 2.67 | 2.04–3.49 | <0.001 | 1.72 | 1.17–2.53 | 0.006 | |
Grade | G1 | 0.73 | 0.49–1.08 | 0.80 | 0.54–1.20 | ||
G2 | 1.00 | 1.00 | |||||
G3 | 1.44 | 1.10–1.88 | 0.001 | 1.32 | 0.95–1.71 | 0.121 | |
Vascular invasion | Negative | 1.00 | 1.00 | ||||
Positive | 1.50 | 1.01–2.22 | 0.045 | 1.47 | 0.79–2.76 | 0.221 | |
Adjuvant treatment | No | 1.00 | 1.00 | ||||
Yes | 2.65 | 1.83–3.82 | <0.001 | 2.19 | 1.49–3.22 | <0.001 | |
Blood transfusion | No | 1.00 | 1.00 | ||||
Yes | 1.92 | 1.03–3.57 | 0.037 | 2.33 | 1.21–4.51 | 0.012 | |
ABO blood group | A | 1.00 | 1.00 | ||||
B | 0.97 | 0.71–1.34 | 0.94 | 0.60–1.47 | |||
O | 1.07 | 0.79–1.47 | 1.06 | 0.67–1.68 | |||
AB | 1.78 | 1.08–2.99 | 0.121 | 2.10 | 1.00–4.41 | 0.215 | |
ABO blood group | O | 1.00 | - | ||||
A/B/AB | 1.04 | 0.78–1.37 | 0.812 | - | |||