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Table 4 Distribution and analysis of preoperative and postoperative factors related to mortality within 1 year after major lower limb amputation in northern Jordan

From: Major lower extremity amputation: a contemporary analysis from an academic tertiary referral centre in a developing community

Preoperative and postoperative variables

Mortality at 1 year

P-value

Yes

N (% from total mortality)

No

N (% from total survival)

Sex

 Male

19 (44.2)

58 (68.2)

0.008*

 Female

24 (55.8)

27 (31.8)

Age (mean ± SE, years)

68.9 ± 1.5

60.1 ± 1.4

< 0.001*

Comorbidities

 Hypertension

43 (100.0)↑↑

60 (73.2)

< 0.001*

 Diabetes mellitus

40 (87.1)

74 (93.0)

NS

 Ischaemic heart disease

21 (50.0)

40 (48.2)

NS

 Congestive heart failure

16 (39.0)

25 (30.1)

NS

 Stroke

18 (42.9)↑↑

16 (19.0)

0.005*

 Chronic kidney disease

16 (38.1)↑

19 (22.4)

0.049*

 Dyslipidaemia

28 (65.1)

56 (65.9)

NS

 Buerger’s disease

2 (4.7)↓

15 (19.0)

0.023*

Indication for amputation

 Acute limb ischaemia

5 (11.6)

11 (12.6)

NS

 Chronic limb ischaemia

3 (7.0)

17 (20.0)

 Diabetic foot syndrome

35 (81.4)

57 (67.1)

Ulceration

39 (90.7)

70 (82.4)

NS

Laboratory values

 Albumin

27.2 ± 1.1

30.6 ± 1.0

0.023*

 HbA1c

8.6 ± 0.4

9.0 ± 0.3

NS

Level of amputation

 BKA

33 (76.7)

68 (80.0)

NS

 AKA

10 (23.3)

17 (20.0)

Side

 Right

25 (58.1)

42 (49.4)

NS

 Left

18 (41.9)

43 (50.6)

Bilateral amputation

14 (32.6)

22 (25.9)

NS

Revision

2 (4.7)

11 (12.9)

NS

Vascular surgeon

21 (48.8)

51 (60.0)

NS

LOS (mean ± SE, days)

6.1 ± 0.6

7.4 ± 0.7

NS

  1. SE Standard error, HbA1c Haemoglobin A1c, BKA Below-knee amputation, AKA Above-knee amputation, LOS Length of stay, NS Not significant
  2. *Statistically significant difference
  3. ↑Significantly greater than expected (p < 0.05)
  4. ↑↑Significantly greater than expected (p < 0.001)
  5. ↓Significantly less than expected (p < 0.05)