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Table 1 Comparison of clinicopathological characteristics and perioperative outcomes between OPD and LAPD groups

From: Laparoscopic assisted pancreaticoduodenectomy: an important link in the process of transition from open to total laparoscopic pancreaticoduodenectomy

Variable

All PDs

OPD(n = 97)

LAPD(n = 36)

P

Age, median (range), yrs

59 (14–79)

58 (14–79)

60.5 (17–78)

0.147

Male sex

78 (58.6)

59 (60.8)

19 (52.8)

0.402

ASA ratio (I: II: III)

18:103:12

16:70:11

2:33:1

0.068

BMI, mean (SD), kg/m2

22.26 (2.87)

22.5 (2.9)

21.8 (2.7)

0.211

Abdominal/Back Pain

70 (52.6)

55 (56.7)

15 (41.7)

0.123

Jaundice

60 (45.1)

45 (46.4)

15 (41.5)

0.627

Preoperative ALB

40.4 (6.7)

40.7 (4.4)

41.8 (4.7)

0.234

Preoperative HGB

127.3 (19.7)

128.3 (16.6)

127.9 (15.7)

0.895

Lesion major diameter, median (range), cm

3.0 (0.2–12.5)

3.0 (0.2–12.5)

2.65 (0.4–6.5)

0.594

PDAC

58 (43.6)

47 (48.5)

11 (30.6)

0.064

Pylorus-preserving PD

28 (21.1)

17 (17.5)

11 (30.6)

0.101

OT, median (range), min

320 (210–585)

305 (210–585)

372 (257–525)

< 0.001

EBL, median (range), ml

400 (50–2400)

500 (50–2400)

300 (50–1300)

0.002

Intraoperative blood transfusion

36 (27.1)

30 (30.9)

6 (16.7)

0.100

Conversion to open

6 (16.7%)

30-Day mortality

0

0

0

90-Day mortality

0

0

0

Grade B/C POPF

1 (0.8)

1 (1.0)

0 (0)

1.000

DGE

30 (22.6)

22 (22.7)

8 (22.2)

0.955

Major complication (Grade III-V)

40 (30.1)

30 (30.9)

10 (27.8)

0.725

 Grade I

8 (6.0)

6 (6.2)

2 (5.6)

1.000

 Grade II

27 (20.3)

20 (20.6)

7 (7.3)

0.881

 Grade III

37 (27.8)

28 (28.9)

9 (25.0)

0.658

 Grade IV

3 (2.3)

2 (2.1)

1 (2.8)

1.000

 Grade V

0 (0)

0 (0)

0 (0)

Time to first flatus, median (range), days

4 (1–9)

4 (1–9)

3 (2–8)

0.007

Re-operation

5 (3.8)

4 (4.1)

1 (2.8)

1.000

Postoperative LOS, median (range), days

12 (7–51)

12 (7–51)

11.5 (7–35)

0.472

  1. Values in parentheses are percentages unless indicated otherwise; Abbreviations: ALB Albumin, ASA American Society of Anesthesiologists, BMI body mass index, DGE delayed gastric emptying, OT operative time, EBL estimated blood loss, HGB Hemoglobin, LAPD laparoscopic assisted pancreaticoduodenectomy, LOS length of hospital stay, OPD open pancreaticoduodenectomy, PD pancreaticoduodenectomy, PDAC Pancreatic ductal adenocarcinoma, POPF postoperative pancreatic fistula