Table 4 Comparison of patient characteristics between Low and High PNI groups
PNI median | Low PNI (PNI < 37: n = 17) 33.6 (26.0–36.9) | High PNI (PNI ≥ 37: n = 172) 45.9 (37.3–60.0) | p value |
|---|---|---|---|
Age | 68 (47–81) | 70 (41–85) | n.s |
Sex (male / female) | 11/6 | 142/30 | n.s |
BMI | 23.2 (15.6–29.6) | 22.1 (13.2–32.5) | n.s |
Lymphocyte count (/mm3) | 710 (320–2260) | 1480 (350–2950) | < 0.001 |
Neutrophil count (/mm3) | 2420 (910–8780) | 3030 (820–8680) | n.s |
Albumin (g/dl) | 2.9 (2.3–3.4) | 3.8 (2.7–5.3) | < 0.001 |
Total bilirubin (mg/dl) | 0.6 (0.4–1.6) | 0.6 (0.2–2.5) | n.s |
Platelet count (103/µl) | 13.4 (4.4–37.9) | 18.6 (4.1–219.0) | n.s |
PT-INR | 1.16 (0.87–1.41) | 1.05 (0.88–1.34) | < 0.001 |
Child–Pugh A/B/C | 11 / 6 / 0 | 167 / 5 / 0 | < 0.001 |
ICG R15 (%) | 23.9 (6.3–49.9) | 12.6 (0.3–76.3) | 0.007 |
LHL15 | 0.87 (0.68–0.96) | 0.94 (0.76–0.99) | < 0.001 |
ALBI grade 1 / 2 / 3 | 0 / 12 / 5 | 85 / 87 / 0 | < 0.001 |
NLR | 3.98 (0.86–14.16) | 2.00 (0.52–12.8) | 0.004 |
PLR | 223 (49–486) | 134 (23–1685) | n.s |
Underlying liver disease | 0.03 | ||
Hepatitis B | 2 (12%) | 24 (14%) | |
Hepatitis C | 12 (70%) | 66 (38%) | |
Non-B non-C | 3 (18%) | 82 (48%) | |
Liver pathology | n.s | ||
Normal liver | 1 (6%) | 23 (15%) | |
Chronic hepatitis | 5 (29%) | 72 (47%) | |
Liver cirrhosis | 11 (65%) | 59 (38%) |