Characteristics | Before PSM(n = 1331) | P | After PSM(n = 668) | P | ||
---|---|---|---|---|---|---|
Elderly | Nonelderly | Elderly | Nonelderly | |||
n = 363 | n = 968 | n = 334 | n = 334 | |||
Age # | 70.38 (4.46) | 51.55 (8.56) | < 0.001 | 70.25 (4.47) | 52.16 (8.66) | < 0.001 |
Male sex | 298 (82.09) | 829 (85.64) | 0.130 | 274 (82.04) | 277 (82.93) | 0.839 |
ASA score > 2 | 124 (34.16) | 184 (19.01) | < 0.001 | 114 (34.13) | 68 (20.30) | < 0.001 |
Overweight | 107 (29.48) | 337 (34.81) | 0.076 | 97 (29.04) | 95 (28.44) | 0.932 |
Comorbidity | 177 (48.76) | 177 (18.29) | < 0.001 | 162 (48.50) | 49 (14.67) | < 0.001 |
AFP > 400 µg/l | 92 (25.34) | 361 (37.29) | < 0.001 | 91 (27.25) | 88 (26.35) | 0.861 |
ALT > 40 U/L | 117 (32.23) | 404 (41.74) | 0.002 | 115 (34.43) | 111 (33.23) | 0.806 |
AST > 40 U/L | 163 (44.90) | 424 (43.80) | 0.765 | 147 (44.01) | 147 (44.01) | 0.999 |
HBV infection | 300 (82.64) | 859 (88.74) | 0.004 | 283 (84.73) | 285 (85.33) | 0.914 |
Cirrhosis | 165 (45.45) | 432 (44.63) | 0.835 | 148 (44.31) | 147 (44.01) | 0.999 |
Portal hypertension | 113 (31.13) | 374 (38.64) | 0.014 | 108 (32.34) | 104 (31.14) | 0.803 |
Child‒Pugh grade B | 11 (3.03) | 51 (5.27) | 0.114 | 11 (3.29) | 10 (2.99) | 0.999 |
BCLC staging B/C | 109 (30.03) | 364 (37.60) | 0.012 | 98 (29.34) | 101 (30.24) | 0.866 |
Intraoperative variables | ||||||
Open operative approach | 283 (77.96) | 819 (84.61) | 0.005 | 264 (79.04) | 268 (80.24) | 0.773 |
Margin width < 1 cm | 63 (17.36) | 111 (11.47) | 0.006 | 49 (14.67) | 50 (14.97) | 0.999 |
Blood loss > 600ml | 29 (7.99) | 76 (7.85) | 0.999 | 25 (7.49) | 29 (8.68) | 0.670 |
Intraoperative blood transfusion | 84 (23.14) | 212 (21.90) | 0.682 | 79 (23.65) | 85 (25.45) | 0.653 |
Operation duration > 180 min | 234 (64.46) | 757 (78.20) | < 0.001 | 226 (67.66) | 224 (67.07) | 0.934 |
Anatomical hepatectomy | 190 (52.34) | 443 (45.76) | 0.038 | 170 (50.90) | 166 (49.70) | 0.816 |
Extended hemihepatectomy | 56 (15.43) | 179 (18.49) | 0.220 | 53 (15.87) | 61 (18.26) | 0.472 |
Occlusion | 200 (55.10) | 543 (56.10) | 0.791 | 183 (54.79) | 196 (58.68) | 0.349 |
Tumor variables | ||||||
Macrovascular invasion | 25 (6.89) | 105 (10.85) | 0.039 | 24 (7.19) | 18 (5.39) | 0.425 |
MVI | 110 (30.30) | 306 (31.61) | 0.695 | 104 (31.14) | 87 (26.05) | 0.171 |
Satellite nodules | 34 (9.37) | 163 (16.84) | 0.001 | 33 (9.88) | 30 (8.98) | 0.791 |
Poor Tumor differentiation | 281 (77.41) | 629 (64.98) | < 0.001 | 254 (76.05) | 253 (75.75) | 0.999 |
Incomplete tumor envelope | 30 (8.26) | 168(17.36) | < 0.001 | 29 (8.68) | 30 (8.98) | 0.999 |
Tumor diameter > 5 cm | 167 (46.01) | 427 (44.11) | 0.577 | 153 (45.81) | 142 (42.51) | 0.436 |