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Table 2 Univariate analysis carried out with different Ki67 fraction cut-off points to find those best dividing the patients according to survival

From: Combined utility of Ki-67 index and tumor grade to stratify patients with pancreatic ductal adenocarcinoma who underwent upfront surgery

Ki67 cut-off point

n

HR (95% CI)

P

Continuous variable

1182

1.006 (1.002–1.010)

0.005

≥ 20% vs. <20%

1076 v.s.106

1.430 (1.090–1.876)

0.010

≥ 30% vs. <30%

980 vs. 202

1.359 (1.112–1.661)

0.003

≥ 40% vs. <40%

795 vs. 387

1.296 (1.105–1.520)

0.001

≥ 50% vs. <50%

546 vs. 636

1.062 (0.914–1.233)

0.433

≥ 60% vs. <60%

339 vs. 843

1.109 (0.936–1.313)

0.234

≥ 70% vs. <70%

140 v.s.1042

1.223 (0.957–1.562)

0.107

  1. Abbreviations: CI Confidence interval, HR Hazard ratio