| MIS | OPEN | p-value |
---|---|---|---|
 | N = 3,601 | N = 5,863 |  |
Surgical resection |  < 0.001 | ||
 Anterior resection | 1,928 (53.5) | 2,791 (47.6) |  |
 Abdominoperineal resection | 1,388 (38.5) | 2,260 (38.5) |  |
 Hartmann's procedure | 284 (7.9) | 812 (13.8) |  |
 Diverting ileostomya | 1,420 (73.7) | 2,229 (80.0) |  < 0.001 |
 MIS converted to open | 523 (14.5) | n/a |  |
 missing | 6 (0.2) | n/a |  |
 Operating time in minutes, median (IQR) | 333.5 (252.5, 414.5) | 277.0 (190.5, 363.5) |  < 0.001 |
 missing | 22 (0.6) | 61 (1.0) |  |
 Intraoperative bleeding in ml, median (IQR) | 100 (25.0, 175.0) | 350(300.0, 400.0) |  < 0.001 |
 missing | 104 (2.9) | 113 (1.9) |  |
 Perforation | 132 (3.7) | 301 (5.1) | 0.001 |
 perforations close to tumour | 61 (1.7) | 158 (2.7) | 0.134 |
T-stage (yp/pTb) |  < 0.001 | ||
 T0 | 124 (3.5) | 224 (3.9) |  |
 T1 | 363 (10.2) | 435 (7.5) |  |
 T2 | 1,157 (32.6) | 1,560 (26.9) |  |
 T3 | 1,765 (49.7) | 3,011 (52.0) |  |
 T4 | 140 (3.9) | 562 (9.7) |  |
 missing | 52 (1.4) | 71 (1.2) |  |
Nodal status (yp/pNc) | 0.001 | ||
 N0 | 2,237 (62.1) | 3,459 (59.0) |  |
 N1 | 948 (26.3) | 1,601 (27.3) |  |
 N2 | 360 (10.0) | 724 (12.3) |  |
 missing | 56 (1.5) | 79 (1.3) |  |
yp/pTNMd |  < 0.001 | ||
 I | 1,095 (30.4) | 1,518 (25.9) |  |
 II | 868 (24.1) | 1,572 (26.8) |  |
 III | 1,144 (31.7) | 1,934 (33.0) |  |
 IV | 139 (3.9) | 506 (8.6) |  |
 missing | 355 (9.8) | 333 (5.7) |  |
 Tumour deposit | 475 (13.2) | 921 (15.7) |  < 0.001 |
 missing | 148 (4.1) | 470 (8.0) |  |
 Vascular invasion – yes | 920 (25.5) | 1,514 (25.8) | 0.927 |
 missing | 145 (4.0) | 157 (2.7) |  |
 Perineural invasion – yes | 671 (18.6) | 1,116 (19.0) | 0.700 |
 missing | 146 (4.0) | 213 (3.6) |  |
 Cancer differentiation – high grade | 440 (12.2) | 813 (13.9) | 0.001 |
 missing | 287 (8.0) | 754 (12.9) |  |