Table 4 Primary and secondary outcomes for patients who were diagnosed with rectal cancer in Sweden 2012–2018 and underwent surgical resection MIS vs OPEN. Unadjusted and adjusted results including unweighted and weighted analysis

CRM^a < 1 mm

135 (3.8)

315 (5.4)

0.678 (0.551, 0.833)

 < 0.001

0.817 (0.641, 1.041)

0.101

0.805 (0.624, 1.038)

0.095

missing

294 (8.2)

532 (9.1)

R1^b

100 (2.8)

259 (4.4)

1.606 (1.270, 2.031)

 < 0.001

1.268 (0.969, 1.660))

0.083

1.318 (0.987, 1.761)

0.061

missing

163 (4.5)

220 (3.7)

DRM^c < 1 mm

9 (0.2)

12 (0.2)

1.236 (0.520, 2.937)

0.631

1.185 (0.420, 3.342)

0.748

1.108 (0.405, 3.027)

0.842

missing

279 (7.7)

391 (6.7)

30-day mortality

19 (0.5)

70 (1.2)

0.439 (0.264, 0.730)

0.002

0.490 (0.276, 0.868)

0.014

0.513 (0.287, 0.920)

0.025

missing

0 (0)

0 (0)

90-day mortality

37 (1.0)

120 (2.0)

0.497 (0.343, 0.720)

 < 0.001

0.488 (0.320, 0.744)

0.001

0.487 (0.318, 0.744)

0.001

missing

0 (0)

0 (0)

Anastomotic leak

166 (4.6)

231 (3.9)

0.115 (0.961, 1.445)

0.115

1.095 (0.862, 1.393)

0.456

0.968 (0.771, 1.214)

0.776

Re-operation 30-days

327 (9.08)

532 (9.07)

0.990 (0.866, 1.157)

0.990

1.054 (0.894, 1.244)

0.530

0.940 (0.794, 1.113)

0.473

missing

23 (0.6)

37 (0.6)

Re-admission 30-days

807 (22.4)

1,545 (26.3)

0.807 (0.732, 0.890)

 < 0.001

0.770 (0.690, 0.860)

 < 0.001

0.855 (0.762, 0.959)

0.008

missing

0 (0)

0 (0)

Re-admission 90-days

1,235 (34.3)

2,332 (39.8)

0.790 (0.725, 0.862)

 < 0.001

0.800 (0.725, 0.883)

 < 0.001

0.853 (0.771, 0.944)

0.002

missing

0 (0)

0 (0)

 < 12 lymph nodes in specimen

423 (11.7)

791 (13.5)

1.172 (1.033, 1.330)

0.014

1.047 (0.903, 1.213)

0.543

1.092 (0.937, 1.273)

0.257

missing

66 (1.8)

108 (1.8)