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Table 2 Summary of Studies Included in Literature Review

From: Quality of life after emergency laparotomy: a systematic review

Author and year

Method

Average age (years)

Preoperative QOL

N (eligible

Patients)

Follow up (months)

Mortality

Postoperative

QOL

QOL measurement tool

Baseline/Comparator

Population

Components with significant differences

Questionnaire

Response Rate (%)

Witte et al. 2022 [22]

Retrospective

71

No

64

49.4

60.9% in hospital

Yes

EQ 5D

Reference population

Not available

19

Alder et al. 2021 [8]

Retrospective

79

Yes

153

19

35.3% all-cause mortality at 19 months post-operatively

Yes

SF-36

General population

Physical functioning reduced Energy and fatigue worse

Social functioning decreased

64.7

Purcell et al. 2021 [13]

Prospective

39

Yes

117

1

2.6% in hospital

Yes

PROMIS-25

Preoperative status (questionnaire administered up to post-op day 1)

Fatigue increased

Mobility improved

Pain worsened

65.8

Saunders et al. 2021 [14]

Prospective

65.5

Yes

129

12

Not reported

Yes

EQ 5D

WHODAS

Preoperative status (questionnaire administered at post-op day 5)

Not available

54

Tolstrup et al. 2019 [15]

Prospective

69

No

605

60

Not reported

Yes

GIQLI

Patients with no chronic

post-operative pain

Core symptoms worse

Physical items worse

Psychological items worse

Social function worse

Disease specific items worse

73

Kwong et al. 2018 [19]

Retrospective

65

Yes

255

3

Retrospective using same patient group, only alive patients included in study

Yes

EQ 5D3L

GIQLI

Preoperative status (retrospective questionnaire regarding preadmission health status)

Improved symptoms

Reduced social functioning

74.1

Li et al. 2017 [16]

Prospective

65.3

Yes

50

3

Not reported

Yes

Unspecified

Preoperative status (timing of questionnaire not specified)

Not available

100

Jeppesen et al. 2016 [20]

Retrospective

61

No

110

37

Retrospective, only alive patients included in study

Yes

GIQLI

Patients with no chronic

post-operative pain

Symptoms worse

Emotions worse

Medical treatment increased

82

Boer et al. 2007 [17]

Retrospective

63

No

155

6

Retrospective, only alive patients selected for inclusion

Yes

EQ 5D

EQVAS

Healthy reference population

Mobility worse

Self-care reduced

Daily activity reduced

Pain worse

Mood worse

84

Joneja et al. 2004 [18]

Prospective

41.5

Yes

51

6

Not reported

Yes

GIQLI

Preoperative status (questionnaire completed before surgery)

Improved disease specific symptoms

Psychological symptoms improved

Physical and social factors improved

84.3

Scheingraber et al. 2002 [21]

Retrospective

54

No

60

unknown

46% in hospital, 10% at home (unspecified time post-operatively)

Yes

SF-36

Matched pair in normal population

Physical function worse

Physical role worse

Mental health improved

97