Table 1 Clinical characteristics and haematological indices of 198 patients
Variables | All | Good response | Poor response | P value |
|---|---|---|---|---|
Gender |  |  |  | P = 0.818 |
Female | 60(30.3%) | 19(29.2%) | 41(30.8%) | Â |
Male | 138(69.7%) | 46(70.8%) | 92(69.2%) | Â |
Age |  |  |  | P = 0.141 |
≤60 years | 104(52.5%) | 39(60.0%) | 65(48.9%) |  |
>60 years | 94(47.5%) | 26(40.0%) | 68(51.1%) | Â |
BMI |  |  |  | P = 0.969 |
≤25 | 107(54%) | 35(53.8%) | 72(54.1%) |  |
>25 | 91(46%) | 30(46.2%) | 61(45.9%) | Â |
Clinical T stage |  |  |  | P = 0.523 |
T2-3 | 131(66.2%) | 45(69.2%) | 86(64.7%) | Â |
T4 | 67(33.8%) | 20(30.8%) | 47(35.3%) | Â |
Clinical N stage |  |  |  | P = 0.092 |
N- | 6(3%) | 4(6.2%) | 2(1.5%) | Â |
N+ | 192(97%) | 61(93.8%) | 131(98.5%) | Â |
Length of newly diagnosed tumour |  |  |  | P = 0.511 |
≤5 cm | 100(50.5%) | 35(53.8%) | 65(48.9%) |  |
>5Â cm | 98(49.5%) | 30(46.2) | 68(51.1%) | Â |
distance from the lower border of the tumour to the anal verge |  |  |  | P = 0.265 |
≤5 cm | 59(29.8%) | 16(24.6%) | 43(32.3%) |  |
>5Â cm | 139(70.2%) | 49(75.4%) | 90(67.7%) | Â |
CEA |  |  |  | P = 0.018 |
≤5 µg/L | 98(49.5%) | 40(61.5%) | 58(43.6%) |  |
>5 µg/L | 100(50.5%) | 25(38.5%) | 75(56.4%) |  |
CA199 |  |  |  | P = 0.582 |
≤40U/L | 173(87.4%) | 58(89.2%) | 115(86.5%) |  |
>40U/L | 25(12.6%) | 7(10.8%) | 18(13.5%) | Â |
CA724 |  |  |  | P = 0.747 |
≤6U/L | 152(76.8%) | 49(75.4%) | 103(77.4%) |  |
>6U/L | 46(23.2%) | 16(24.6%) | 30(22.6%) | Â |
NLR (median) | 4.83 ± 3.40 | 4.00 ± 1.94 | 5.23 ± 3.87 | P = 0.017 |
PLR (median) | 284.06 ± 147.38 | 267.52 ± 159.25 | 292.14 ± 141.14 | P = 0.292 |
LMR (median) | 2.19 ± 1.04 | 2.25 ± 1.11 | 2.15 ± 1.01 | P = 0.559 |
Fib (median) | 3.30 ± 0.75 | 3.18 ± 0.72 | 3.37 ± 0.76 | P = 0.090 |
D-dimer (median) | 0.26 ± 0.37 | 0.25 ± 0.37 | 0.26 ± 0.37 | P = 0.890 |
SII (median) | 976.21 ± 970.43 | 743.44 ± 602.26 | 1089.97 ± 1090.82 | P = 0.018 |
ALI (median) | 279.76 ± 147.15 | 312.76 ± 153.46 | 263.64 ± 141.77 | P = 0.032 |
PNI (median) | 45.02 ± 5.28 | 45.52 ± 3.77 | 44.77 ± 5.87 | P = 0.280 |
SIRI (median) | 1.87 ± 1.46 | 1.49 ± 0.84 | 2.06 ± 1.66 | P = 0.009 |