Table 3 Univariate and multivariate analysis of overall survival in 198 patients

Gender

P = 0.697

Female

1

Male

0.856(0.391,1.873)

Age

P = 0.186

≤60 years

1

>60 years

1.637(0.788,3.399)

BMI

P = 0.156

≤25

1

>25

0.583(0.277,1.228)

Clinical T stage

P = 0.429

T2-3

1

T4

1.343(0.646,2.791)

Clinical N stage

P = 0.254

-

1

 N+

0.434(0.103,1.824)

Length of newly diagnosed tumour

P = 0.715

≤5 cm

1

>5 cm

1.035(0.838,1.278)

Distance from the lower border of the tumour to the anal verge

P = 0.382

≤5 cm

1

>5 cm

1.459(0.626,3.402)

Depth of newly diagnosed tumour

1.515(1.033,2.223)

P = 0.034

1.406(0.962,2.055)

P = 0.078

CEA

P = 0.377

≤5 µg/L

1

>5 µg/L

1.385(0.672,2.855)

CA199

P = 0.001

P = 0.002

≤40U/L

1

1

>40U/L

3.740(1.707,8.194)

3.563(1.624,7.814)

CA724

P = 0.184

≤6U/L

1

>6U/L

1.674(0.783,3.578)

NLR

P = 0.089

≤4.39

1

>4.39

1.873(0.910,3.856)

SII

P = 0.092

≤707.65

1

>707.65

1.923(0.900,4.109)

SIRI

P = 0.004

P = 0.009

≤2.53

1

1

>2.53

2.870(1.393,5.910)

2.621(1.269,5.413)