Table 4 Univariate and multivariate analysis of disease-free survival in 198 patients

Gender

P = 0.824

Female

1

Male

1.066(0.609,1.868)

Age

P = 0.709

≤60 years

1

>60 years

1.101(0.666,1.820)

BMI

P = 0.156

≤25

1

>25

0.689(0.412,1.153)

Clinical T stage

P = 0.458

T2-3

1

T4

1.218(0.724,2.049)

Clinical N stage

P = 0.993

-

1

 N+

1.007(0.246,4.124)

Length of newly diagnosed tumour

P = 0.690

≤5 cm

1

>5 cm

1.108(0.670,1.833)

Distance from the lower border of the tumour to the anal verge

P = 0.881

≤5 cm

1

>5 cm

1.043(0.601,1.809)

Depth of newly diagnosed tumour

1.341(1.017,1.770)

P = 0.038

1.277(0.960,1.699)

P = 0.093

CEA

P = 0.836

≤5 µg/L

1

>5 µg/L

0.948(0.573,1.570)

CA199

P = 0.227

≤40U/L

1

>40U/L

1.519(0.771,2.994)

CA724

P = 0.033

P = 0.122

≤6U/L

1

1

>6U/L

1.789(1.047,3.057)

1.539(0.891,2.658)

NLR

P = 0.053

≤4.39

1

>4.39

1.641(0.993,2.714)

SII

P = 0.051

≤707.65

1

>707.65

1.675(0.998,2.812)

SIRI

P = 0.001

P = 0.005

≤2.53

1

1

>2.53

2.381(1.411,4.018)

2.143(1.259,3.650)